Hotels in Irene

Free cancellation options if plans change
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Check prices for these dates

Tonight
Feb 14 - Feb 15
Tomorrow
Feb 15 - Feb 16
This weekend
Feb 14 - Feb 16
Next weekend
Feb 21 - Feb 23

Where to stay in Irene?

Holiday Inn Express & Suites Yankton by IHG
Exterior

Holiday Inn Express & Suites Yankton by IHG

2.5 star property
9.2 out of 10, Wonderful, (380)
The price is $121
includes taxes & fees
$110 per night
Mar 5 - Mar 6
Holiday Inn Express & Suites Yankton by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
On a rooftop patio

Use code VALENPOWER for an extra 10% off your next getaway

One Key™ members get an extra 10% off hotels, book by Feb 17, travel between Feb 6 through Aug 31 (US customers only).*T&Cs apply

Learn more about Irene

You can explore the area's natural beauty at Lincoln Park during your stay.

See all hotels in Irene

Frequently asked questions

What accommodations do travelers recommend in Irene?
Guests like Parkview Cottage ~ Charming Tiny Home ~ Queen Bed!.
Can I book refundable hotels in Irene?
If you’re looking for the flexibility to change your plans to Irene, most accommodations provide refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Irene be like during my vacation?
July and August are typically the warmest months in Irene when the average temp is 72°F. January and February are the coldest months when the average temperature is 26°F. June and May are the months with the most rain.
Why should I book my Irene accommodation with Hotels.com?
There are lots of reasons to book your Irene trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.