Hotels in Santee

your current months are December, 2024 and January, 2025.
December 2024
January 2025

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Where to stay in Santee?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santee

Learn more about Santee

Notable for its golfing, Santee features attractions such as Santee Cooper Country Club and Santee National Golf Club. Visitors to this welcoming city speak highly of the restaurants whereas sights include Santee State Park and Lake Marion.

Frequently asked questions

Can I book refundable accommodations in Santee?
If you want the flexibility to change your plans to Santee, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Santee if I want a vacation rental instead of a hotel?
Browse 9 vacation homes on our site. You also might want to book one of 81 condos for your trip.
What will the weather in Santee be like during my vacation?
July and August are typically the warmest months in Santee when the average temp is 79°F. January and February are the coldest months when the average temperature is 52°F. August and July are the months with the most rain.
Why should I book my Santee hotel with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.