Hotels in Picayune

your current months are January, 2025 and February, 2025.
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February 2025
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Where to stay in Picayune?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Picayune

Learn more about Picayune

Picayune is well-known for its attractions such as Crosby Arboretum and Millbrook Country Club.

Frequently asked questions

What accommodations do travelers recommend in Picayune?
Holiday Inn Express Picayune-Stennis Space Center, an IHG Hotel, Heritage Inn Picayune and Days Inn by Wyndham Picayune are all properties that our guests really like.
Can I book a refundable hotel in Picayune?
If you’re looking for the flexibility to change your travel plans to Picayune, most accommodations provide refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Picayune if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, browse our selection of 13 vacation homes. You can also consider one of the 6 cottages for your trip.
What will the weather in Picayune be like during my visit?
August and July are typically the warmest months in Picayune when the average temp is 80°F. January and December are the coldest months when the average temperature is 55°F. August and July are the months with the most rain.
Why should I book my Picayune hotel through Hotels.com?
There are lots of reasons to book your Picayune trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.