Hotels in South San Diego

your current months are December, 2024 and January, 2025.
December 2024
January 2025

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Where to stay in South San Diego?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in South San Diego

Top landmarks in South San Diego

Frequently asked questions

Can I book refundable accommodations in South San Diego?
If you need the flexibility to change your plans to South San Diego, most hotels provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in South San Diego if I want a vacation home instead of a traditional hotel?
If you want to find a good alternative to a hotel, review our selection of 140 vacation homes. In addition, there are 26 apartments and 68 condos.
Why should I book my South San Diego hotel with Hotels.com?
There are plenty of reasons to book your South San Diego travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.