Hotels in Southwest Florida

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Where to stay in Southwest Florida?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southwest Florida, FL

Showing deals for:Apr 4 - Apr 6

Top neighborhoods in Southwest Florida

Top landmarks in Southwest Florida

Learn more about Southwest Florida

Southwest Florida is well-known for its natural beauty and seaside while top attractions include Siesta Key Beach, Key West Express, and Venice Beach. Visitors highlight this beachside city's golfing while sights include Lido Beach and St. Armands Circle.

Fort Myers Beach featuring a sandy beach as well as a large group of people

Frequently asked questions

Can I book a refundable hotel in Southwest Florida?
If you want the flexibility to change your travel plans to Southwest Florida, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Southwest Florida if I want a vacation home instead of a traditional hotel?
If you’re looking for a good alternative to a hotel, review our selection of 17234 vacation homes. In addition, there are 1796 apartments and 11525 condos.
Why should I book my Southwest Florida accommodation with Hotels.com?
There are plenty of reasons to book your Southwest Florida travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.