Photo by Matt Mateo

Hotels in Melrose

your current months are December, 2024 and January, 2025.
December 2024
January 2025

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Where to stay in Melrose?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Melrose

Learn more about Melrose

The region around Melrose is home to attractions such as Santa Fe Lake and Waldo Motorsports.

Melrose, FL
Lake Santa Fe
Photo by Matt Mateo
Open Photo by Matt Mateo

Frequently asked questions

What hotels do travelers recommend in Melrose?
Guests like Lake living close to Gainesville, UF Health and University of Florida.
Can I book a refundable hotel in Melrose?
If you’re looking for the flexibility to change your travel plans to Melrose, most accommodations provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where can I stay in Melrose if I want a vacation home instead of a traditional hotel?
If you want to find a good alternative to a hotel, browse our selection of 20 vacation homes.
What will the weather in Melrose be like during my trip?
July and August are typically the warmest months in Melrose when the average temp is 80°F. January and February are the coldest months when the average temperature is 60°F. August and July are the months with the most rain.
Why should I book my Melrose accommodation with Hotels.com?
There are lots of reasons to book your Melrose trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.