Hotels in Main Street Hyannis

your current months are December, 2024 and January, 2025.
December 2024
January 2025

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Where to stay in Main Street Hyannis?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Main Street Hyannis

Frequently asked questions

What accommodations do travelers like in Main Street Hyannis?
Hyannis Inn and Hyannis Plaza Hotel are a couple of accommodations that are popular with guests.
Can I book refundable hotels in Main Street Hyannis?
If you want the flexibility to change your plans to Main Street Hyannis, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Main Street Hyannis if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, review our selection of 9 vacation homes.
What will the weather in Main Street Hyannis be like during my visit?
The warmest months in Main Street Hyannis are usually August and July with an average temp of 67°F. February and January are the chilliest months when the average temp is 37°F. The rainiest months are October and December.
Why should I book my Main Street Hyannis hotel through Hotels.com?
There are plenty of reasons to book your Main Street Hyannis travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.