Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Cape Girardeau on Hotels.com. These Cape Girardeau hotels consistently deliver on comfort, location and traveler experience. Last updated on .
Hotels in Cape Girardeau
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Top 5 hotels in Cape Girardeau at a glance
- Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
- The Riverview — 4-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
- Pear Tree Inn Cape Girardeau West — 2.5-star hotel in Cape Girardeau. Guest rating: 9.0/10 — Wonderful.
- Drury Inn & Suites Cape Girardeau — 3-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG — 2.5-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
Where to stay in Cape Girardeau?

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
$100 nightly
The price is $113
Jul 5 - Jul 6
Total with taxes and fees

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (612 reviews)
$131 nightly
The price is $148
Jun 29 - Jun 30
Total with taxes and fees

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,000 reviews)
$72 nightly
The price is $81
Jul 5 - Jul 6
Total with taxes and fees

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
$96 nightly
The price is $108
Jul 2 - Jul 3
Total with taxes and fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
$110 nightly
The price is $124
Jul 5 - Jul 6
Total with taxes and fees

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (525 reviews)
$125 nightly
The price is $142
Jul 12 - Jul 13
Total with taxes and fees

Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHGCape Girardeau
8.0 out of 10, Very Good, (969 reviews)
$85 nightly
The price is $101
Jul 5 - Jul 6
Total with taxes and fees

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (826 reviews)
$106 nightly
The price is $119
Jul 5 - Jul 6
Total with taxes and fees

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (203 reviews)
$93 nightly
The price is $105
Jul 5 - Jul 6
Total with taxes and fees

Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.0 out of 10, Good, (768 reviews)
$68 nightly
The price is $76
Jul 5 - Jul 6
Total with taxes and fees

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (789 reviews)
$93 nightly
The price is $100
Jun 30 - Jul 1
Total with taxes and fees

Comfort Suites Jackson-Cape Girardeau
Comfort Suites Jackson-Cape GirardeauJackson
8.2 out of 10, Very Good, (771 reviews)
$93 nightly
The price is $101
Jun 30 - Jul 1
Total with taxes and fees

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
$82 nightly
The price is $87
Jul 26 - Jul 27
Total with taxes and fees

Town House Inn Cape Giradreau
Town House Inn Cape GiradreauCape Girardeau
6.2 out of 10, (230 reviews)
$78 nightly
The price is $88
Jun 29 - Jun 30
Total with taxes and fees

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (141 reviews)
$89 nightly
The price is $102
Jul 5 - Jul 6
Total with taxes and fees

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,004 reviews)
$106 nightly
The price is $122
Jul 2 - Jul 3
Total with taxes and fees

Town House Inn
Town House InnJackson
7.6 out of 10, Good, (446 reviews)
$88 nightly
The price is $95
Jun 29 - Jun 30
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out hotels with a pool in Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1002)
$110 nightly
The price is $124
Jul 5 - Jul 6
Total with taxes and fees
You may also like pet-friendly hotels in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1006)
$100 nightly
The price is $113
Jul 5 - Jul 6
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Cape Girardeau
Pet friendly
Top landmarks in Cape Girardeau
Learn more about Cape Girardeau
Hugging the Mississippi River, this college town reveals its history through vibrant floodwall murals that transform concrete into an outdoor gallery. Southeast Missouri State University brings youthful energy to streets lined with locally-owned shops and cafes. The River Campus hosts performances in a former seminary with river views. Explore the Cape Girardeau Conservation Nature Center or paddle the Mississippi. Trail of Tears State Park offers hiking paths with panoramic vistas that explain why settlers chose this dramatic spot. The Cape Riverfront Market buzzes with farmers and artisans, while the historic downtown invites exploration with red-brick buildings housing quirky boutiques and restaurants serving hearty Midwestern fare with surprising sophistication.

Check out reviews of Cape Girardeau hotels guests love

Drury Plaza Hotel Cape Girardeau Conference Center
8/10 Good
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